Ajinomoto Heartland, Inc. built a pilot rumen protected lysine production plant
in 2011 in Eddyville, Iowa, near the heart of America’s vast Corn Belt and expanded
it in 2014. With AjiPro®-L now readily available, feed producers
and nutritionists can improve the nutritional balance of their feed formulas while
reducing diet costs.
With amino acids being a part of the food supply chain, Ajinomoto Heartland, Inc.
is focused on product quality and safety. It manages a comprehensive quality management
system (QMS) and is certified to the ISO 9001:2008 standard. Appreciating the environmental
effect of our production facility, Ajinomoto Heartland, Inc. operates to the ISO
AJIPRO®-L DEVELOPMENT TIMELINE • R&D SINCE MID-80s
1st project started
Decision of suspension
Commercial launch in U.S.
Commercial launch in Canada
The first project (1985 – 1999)
- 300+ prototypes utilizing various technologies.
- Project suspended due to the difficulties in achieving Ajinomoto quality and
The second project (2006 – )
- Re-started with a novel, breakthrough technology.
- Focused more on product characterization in order to achieve precise formulation.
- Pilot plant began operations in Eddyville, IA, in April 2011.
- Efficacy and effects validated in U.S.-based universities and the Miner Institute.
- 2ndgeneration introduction in 2014.
- Commercial AjiPro®-L plant built in 2014.
- AjiPro®-L launched in Canada in 2015.
Product Name: AjiPro®-L
Synonyms: Rumen Protected
Restrictions: For Animal
feed only- not for human consumption
Manufacturer and Distributer:
Ajinomoto Heartland, Inc.
1116 Hwy 137
Eddyville, Iowa 52553
641- 969-4551 – Eddyville IA
773-380-7000 – Chicago, IL.
This product contains soy oil
Eye: Avoid contact with
eyes, (inflammation) otherwise non-hazardous.
Ingestion: May produce an allergic reaction
Principle Routes of Exposure: Eyes, inhalation
Composition on ingredients
% by weight
(dry matter basis)
First Aid measures
Eye Contact: Wash eyes immediately with
large amounts of water or saline
Ingestion: Don’t swallow; rinse mouth
with water and drink plenty of water
Flash Point: 540°F (Closed cup)
Auto-ignition Temperature: N/A
Flammable Limits in Air: N/A
Extinguishing Media: Dry Chemical, Foam,
or Carbon Dioxide
Special Fire-Fighting Procedures: Wear
Protective clothing and respiratory protection to protect from fumes of HCL and
Unusual Fire & Explosion Hazards: Not
a fire hazard
Accidental release measures
Methods for cleaning up: Ordinary, same
as food. Dispose of in accordance with all regulations
Handling and Storage
Handling: Recommended to wear gloves and
dust mask if excessive handling is necessary
Storage: Keep away from sources of ignition.
Store in dry conditions in sealed or closed containers
Work Place: Protective equipment: Safety
Exposure controls/ Personal Protection
Hygiene measures: Handle with good industrial
hygiene and safety practice. Wash hands before breaks and at the end of the day.
Protective Equipment: Safety glasses;
wash hands to avoid eye contact.
Physical and Chemical Data
Bulk density: 0.63 – 0.70 grams/cm3
(39.3 – 43.6 lbs/ft3)
Appearance & Odor: Oval/circular, white,
flat beads: slight characteristic odor and taste
Solubility in Water: Insoluble
Percent Volatile: 0%
Evaporation Rate: None
Stability and reactivity
Stability: Stable if stored in dry conditions
at moderate temperature in sealed or closed containers
Conditions to Avoid: Hot and humid environments
Hazardous Decomposition Products: When
heated to decomposition: Carbon monoxide, carbon dioxide, nitrogen oxide, and hydrogen
chloride gas fumes will be emitted
Check with federal, provincial and local regulations
Proper Shipping Name: AjiPro®-L
AAFCO#: 6.11, 33.2, 87.5
Further Information: The above information
is believed to be accurate and represents the best information currently available
to us and shall be used only as a guide. The information in this document is based
on the present state of our knowledge and is applicable to the product regard to
appropriate safety precautions. It does not represent any guarantee of the properties
of the product. Users should make their own investigations to determine the suitability
of the information for their particular purposes. Ajinomoto Heartland, Inc. shall
not be held liable for any damage resulting in the handling or from the contact
with the above product.
Prepared by: Ajinomoto Heartland, Inc. April 2016
SAFETY DATA SHEET
For animal feed only – not for human consumption
PRODUCT DESCRIPTION SHEET
AjiPro®-L [Feed Grade]
Lysine is the first-limiting amino acid, or the co-limiting with methionine, in corn-based diets for high-producing
dairy cows. Ajinomoto Heartland's AjiPro®-L [Feed Grade] contains a minimum of 40% L-Lysine on a dry matter
Corn, which comprises a large portion of dairy cow diets in North America, is low
in lysine. In order to meet the amino acid requirements of high-producing dairy
cows that cannot be met only with microbial protein, high-protein ingredients such
as soybean meal and animal by-product meals are commonly fed. In the past, excess
protein was fed to meet the requirement of the first-limiting amino acid of dairy
cows, which was also the case for swine and poultry. With the commercialization
of L-Lysine, the lysine requirement of monogastric animals has been successfully
met in a cost-effective manner by reducing the amount of costly, high-protein ingredients
that were once fed. Because a similar advantage has been expected when formulating
the dairy cow diets, if lysine could escape the rumen degradation and be efficiently
delivered to the small intestine of cows, development of an effective rumen-protected
lysine product has been desired.
Supplementing lysine in a form of bypass protein has sometimes failed to show the
response to lysine mainly because of (1) impaired microbial protein synthesis caused
by feeding an excess amount of rumen undegradable protein (RUP) and an insufficient
supply of rumen degradable protein (RDP), (2) insufficient supply of metabolizable
lysine from such bypass protein sources due to lower quality than expected, (3)
partitioning the energy more to catabolism of excess amino acids in the liver rather
than to milk and milk protein synthesis, and so on. On the other hand, a large number
of studies have demonstrated that today’s high-producing dairy cows respond to higher
levels of dietary lysine particularly in milk and milk protein production when lysine
was duodenally or abomasally infused or when lysine was supplemented in a form of
rumen protected lysine. This indicates that elevating the proportion of lysine in
total metabolizable protein (MP) supplied to dairy cows would be the most effective
way to improve milk and milk protein production, as it has been well documented
in monogastric nutrition and commonly recognized as "an ideal protein concept."
AjiPro®-L offers dairy nutritionists flexibility and simplicity with feed formulation
practices. AjiPro®-L allows nutritionists to raise the proportion of lysine in total
MP (Lys/MP ratio) without adversely affecting rumen fermentation. AjiPro®-L helps
reduce the use of bypass protein sources in the diet and reduces the excess supply
of protein to dairy cows, which would lead to improved protein utilization efficiency
and, as a consequence, decreased excretion of urinary nitrogen into the environment.
L-Lysine content: 40% minimum on dry matter basis
Dry matter: No less than 95%
Specific gravity: 1.10-1.15 g/cm3
AjiPro®-L is composed of L-Lysine monohydrochloride (6.11 in AAFCO 2011), vegetable
fat (33.2), and soy lecithin (87.5).
PRODUCT DESCRIPTION SHEET